sepsis is a significant health problem with an estimated 750,000 new cases in the usa annually. it is also the third leading cause of death in developed countries, equaling the number of fatalities from acute myocardial infarction. the high sepsis-related mortalities mean there is an urgent need to improve the diagnosis and management of sepsis patients. the aim of this study was the evaluation...

background objective: to evaluate the utility of specific cut-off values for c- reactive protein (crp) and immature-to-total neutrophil ratio (i/t) as screening tests for meningitis in culture negative early onset sepsis (eos). materials and methods retrospective chart review of 97 newborns with culture negative sepsis who had lumbar puncture performed as part of the sepsis evaluation in a leve...

objective(s) in the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. in this study, we aimed to investigate the value of procalcitonin, and c- reactive protein in establishing the diagnosis of neonatal sepsis. materials and methods blood samples were collected at admission from 69 neonates with suspected infection (admitte...

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

introduction early diagnosis of neonatal sepsis is essential for successful treatment. blood culture is a gold standard for diagnosis but the final results are not available until 48-72 hours after culture. interleukin-6 (il-6) as a marker plays a critical role in the induction of c-reactive protein (crp) synthesis in the liver. it has been hypothesized that this cytokine could be detected in b...

Objective(s) In the last few years, serum procalcitonin has been proposed as an early marker of infections in neonates, with varying results. In this study, we aimed to investigate the value of procalcitonin, and C- reactive protein in establishing the diagnosis of neonatal sepsis. Materials and Methods Blood samples were collected at admission from 69 neonates with suspected infection (admi...

OBJECTIVES To evaluate the C-reactive protein serum levels in patients with pulmonary and abdominal sepsis during the first five days of sepsis progression. METHODS The present investigation was a retrospective cohort study conducted at the university hospital with 345 patients who were admitted to the intensive care unit and diagnosed with sepsis of pulmonary or abdominal origin. Serum C-rea...

INTRODUCTION Clinicians are in need of better diagnostic markers in diagnosing infections and sepsis. We studied the ability of procalcitonin, lipopolysaccharide-binding protein, IL-6 and C-reactive protein to identify patients with infection and sepsis. METHODS Plasma and serum samples were obtained on admission from patients with suspected community-acquired infections and sepsis. Procalcit...

Background: Sepsis is a life-threatening infection, responsible for tremendous morbidity, mortality and healthcare expenditure worldwide. characterized by non-specific symptoms clinical diagnosis remains difficult. C Reactive protein (CRP) procalcitonin (PCT) are now days used as surrogate markers of sepsis. Aim: To determine PCT levels in patients with suspected sepsis its correlation CRP tota...

OBJECTIVE To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. METHODS Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis and 15 with clinical sepsis) and 35 healthy controls. Serum and salivary C-reactive protein concentratio...